From puzzle pieces to personalized medicine: how biomarkers tailor cancer therapy
Each person’s cancer has a unique combination of pieces in their puzzle. Partly due to the complexity of everyone’s genetic profile, it is challenging to develop effective one-size-fits-all therapy that targets all the cells within…
A Novel Strategy to Improve Peptide Based Cancer Vaccines through Molecular Mimicry
Cancer remains a leading cause of mortality worldwide. The therapeutic options to treat cancer are often limited, which reduces the chance to successfully treat patients. To tackle this health problem, interventions are developed such as…
Of Mice and Men
By: Milo Molleson
From house mouse to laboratory mouse
The relationship between humans and mice has a long and captivating history. The house mouse, scientifically known as Mus musculus domesticus, has shared our narrative…
mRNA circularization: a means to the two ends
Looking back at mankind’s history, we can see how the concept of circularization influenced the development of our society. Wheels, for example, are one of the most important first human inventions. Yet the concept of…
A history of the RNA world hypothesis
Scientists have been speculating for over 50 years about RNA’s role at the beginning of life. They debate that before depending on DNA, primitive cells relied on RNA. This so-called RNA world would have existed…
Drug repurposing: the solution might be closer than we think
When Sars-CoV-2 spread at the beginning of 2020, scientists started screening libraries full of drugs for possible treatments. This was the moment when the general public was introduced to drug repurposing.