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A cellular railway in motion

Cilia are highly specialised structures that belong to the list of ancestral eukaryotic compartments together with nuclei and mitochondria. They protrude from the surface of nearly all human cells, acting as cellular antennae, sometimes more than one on each cell. Some cilia are involved in motility where they are found in specialised epithelia to facilitate…

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Glial immune response to hazards in the brain in Parkinson’s Disease

Daily actions and thoughts emerge as cells in the central nervous system are constantly sending molecular messengers to adjacent neurons and in this manner executing a steady informational transfer. Glial cells, surrounding neuronal cells, play a crucial role in forming and maintaining the Blood Brain Barrier. Their functions range from homeostatic regulators (astrocytes) to trash…

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The PANDAS gut feeling

"All disease begins in the gut" - Hippocrates Two weeks ago, an 11-year-old boy was sick with pharyngitis, commonly known as a sore throat. He then experiences a sudden onset of violent outbursts and separation anxiety, followed by the development of obsessions, compulsions, motor and vocal tics, irritability, and insomnia1. What could possibly encompass this peculiar…

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High-intensity interval training makes you feel good inside out

Regular physical activity has great health benefits. An active lifestyle is important to maintain since it is associated with a longer healthspan by delaying the onset of many (chronic) diseases [1]. ‘High-Intensity Interval Training’ (HIIT) is a form of physical activity that, as the name already suggests, involves high-intensity bursts of cardio exercise followed by…

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Vu:Sci Magazine