Cilia are highly specialised structures that belong to the list of ancestral eukaryotic compartments together with nuclei and mitochondria. They protrude from the surface of nearly all human cells, acting as cellular antennae, sometimes more than one on each cell. Some cilia are involved in motility where they are found in specialised epithelia to facilitate…
2001- a breakthrough year for geneticists: the year in which the most important biological code was published. Groups from the US, UK, Japan, Germany and China collaborated to publish the first draft sequence of the human genome [1] based on the sequences of anonymous volunteers. And so, the first pieces in the human genetics puzzle…
Daily actions and thoughts emerge as cells in the central nervous system are constantly sending molecular messengers to adjacent neurons and in this manner executing a steady informational transfer. Glial cells, surrounding neuronal cells, play a crucial role in forming and maintaining the Blood Brain Barrier. Their functions range from homeostatic regulators (astrocytes) to trash…
"All disease begins in the gut" - Hippocrates
Two weeks ago, an 11-year-old boy was sick with pharyngitis, commonly known as a sore throat. He then experiences a sudden onset of violent outbursts and separation anxiety, followed by the development of obsessions, compulsions, motor and vocal tics, irritability, and insomnia1. What could possibly encompass this peculiar…
Regular physical activity has great health benefits. An active lifestyle is important to maintain since it is associated with a longer healthspan by delaying the onset of many (chronic) diseases [1]. ‘High-Intensity Interval Training’ (HIIT) is a form of physical activity that, as the name already suggests, involves high-intensity bursts of cardio exercise followed by…
In the United States during the 1950s and the 60s, hallucinogenic compounds were widely used recreationally, as well as in research and therapies for mental disorders. A ban on these compounds during the 1960s essentially halted much of the research on these compounds, despite objections from the scientific community, until the 1990s saw a revival…
A bedtime story to tell there are no monsters hiding under your bed, an allegory about norms and morals, or a chat with your colleagues at the coffee machine on Monday morning about what you did last weekend – they all say something. They all give information. I’d like to introduce you to a form…
A bedtime story to tell there are no monsters hiding under your bed, an allegory about norms and morals, or a chat with your colleagues at the coffee machine on Monday morning about what you did last weekend – they all say something. They all give information. I’d like to introduce you to a form…
You can imagine a neuron in the brain’s cortex, or anywhere else in the body, as a city with incoming freight road networks. Neurons have quite a few inward-bound roads (dendrites) packed with freight that receive signals and converge near their city centers (the cell body), but there is always one exit highway (the axon).…
With the global prevalence of severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2), coronavirus disease 2019 (COVID-19) has affected the lives of billions of people and caused millions of deaths worldwide[1]. How to tame COVID-19 into submission remains quite challenging. But as the old saying goes: all roads lead to Rome, different diseases could share similar pathogenic…