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Science Digest

An ‘unwanted journey’: how the immune microenvironment may contribute to breast cancer

DCIS is a potential breast cancer precursor lesion that occurs in 20-25% of diagnosed breast cancers. The risk factors for DCIS include obesity, lifestyle choices such as smoking, and rarely familial mutation such a BRCA mutations. Not every DCIS progresses to an invasive disease.

August 20, 20230Comments

ByBasti

Science Digest

A cellular railway in motion

Cilia are highly specialised structures that belong to the list of ancestral eukaryotic compartments together with nuclei and mitochondria. They protrude from the surface of nearly all human cells, acting as cellular antennae, sometimes more than one on each cell. Some cilia are involved in motility where they are found in specialised epithelia to facilitate…

August 9, 20230Comments

ByMadison Carr

Science Digest

Lessons learned from the COVID-19 pandemic: a modeling perspective

By: Feline Velthuis During the COVID-19 pandemic, all eyes were on the mathematical models that would tell us how we could control the outbreak, how occupied hospitals would be and if we could celebrate Christmas together. Worldwide, lots of different models were used to make predictions on the development of the outbreak and the impact…

May 15, 20230Comments

ByBasti

Science Digest

Puzzling our roots: What does diversity have to do with genetics and disease?

2001- a breakthrough year for geneticists: the year in which the most important biological code was published. Groups from the US, UK, Japan, Germany and China collaborated to publish the first draft sequence of the human genome [1] based on the sequences of anonymous volunteers. And so, the first pieces in the human genetics puzzle…

January 3, 20230Comments

ByMadison Carr

Science Digest

Glial immune response to hazards in the brain in Parkinson’s Disease

Daily actions and thoughts emerge as cells in the central nervous system are constantly sending molecular messengers to adjacent neurons and in this manner executing a steady informational transfer. Glial cells, surrounding neuronal cells, play a crucial role in forming and maintaining the Blood Brain Barrier. Their functions range from homeostatic regulators (astrocytes) to trash…

November 8, 20220Comments

ByMadison Carr

Science Digest

The PANDAS gut feeling

"All disease begins in the gut" - Hippocrates Two weeks ago, an 11-year-old boy was sick with pharyngitis, commonly known as a sore throat. He then experiences a sudden onset of violent outbursts and separation anxiety, followed by the development of obsessions, compulsions, motor and vocal tics, irritability, and insomnia1. What could possibly encompass this peculiar…

November 1, 20220Comments

ByMadison Carr

Science Digest

High-intensity interval training makes you feel good inside out

Regular physical activity has great health benefits. An active lifestyle is important to maintain since it is associated with a longer healthspan by delaying the onset of many (chronic) diseases [1]. ‘High-Intensity Interval Training’ (HIIT) is a form of physical activity that, as the name already suggests, involves high-intensity bursts of cardio exercise followed by…

October 3, 20220Comments

ByMadison Carr

Science Digest

The psychedelic “reset” mechanism- and how it could treat depression

In the United States during the 1950s and the 60s, hallucinogenic compounds were widely used recreationally, as well as in research and therapies for mental disorders. A ban on these compounds during the 1960s essentially halted much of the research on these compounds, despite objections from the scientific community, until the 1990s saw a revival…

September 20, 20220Comments

ByMadison Carr

Science Digest

Deciphering the developing brain

A bedtime story to tell there are no monsters hiding under your bed, an allegory about norms and morals, or a chat with your colleagues at the coffee machine on Monday morning about what you did last weekend – they all say something. They all give information. I’d like to introduce you to a form…

February 22, 20220Comments

ByMadison Carr

Science Digest

Participatory Narrative Inquiry: Using stories to open up science

December 1, 20210Comments

ByMadison Carr

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